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Endoscopic optical coherence tomography, also intravascular optical coherence tomography is a catheter-based imaging application of optical coherence tomography (OCT). [1] It is capable of acquiring high-resolution images from inside a blood vessel using optical fibers and laser technology .
Endomicroscopy is a technique for obtaining histology-like images from inside the human body in real-time, [1] [2] [3] a process known as ‘optical biopsy’. [4] [5] It generally refers to fluorescence confocal microscopy, although multi-photon microscopy and optical coherence tomography have also been adapted for endoscopic use.
Optical coherence tomogram of a fingertip. It is possible to observe the sweat glands, having "corkscrew appearance" Interferometric reflectometry of biological tissue, especially of the human eye using short-coherence-length light (also referred to as partially-coherent, low-coherence, or broadband, broad-spectrum, or white light) was investigated in parallel by multiple groups worldwide ...
Angle-resolved low-coherence interferometry (a/LCI) is an emerging [when?] biomedical imaging technology which uses the properties of scattered light to measure the average size of cell structures, including cell nuclei. The technology shows promise as a clinical tool for in situ detection of dysplastic, or precancerous tissue.
It is believed [by whom?] that the concept of moving an optical fiber to produce 2D images with confocal sectioning and laser illumination was first proposed for endoscopic applications by Giniunas et al., in 1993. A major advancement of the SFE is rapid scanning and generation of high-quality images using an amplitude-modulated resonating fiber.
The optical system consists of complex microscopic optical instruments, which are difficult to manufacture and assemble. [2] Therefore, the tool is expensive. [3] CLE is mostly used in combination with other techniques instead of replacing conventional endoscopy with biopsy. [7] CLE can only serve as a complementary to the traditional biopsy.
rigid endoscope: A rigid endoscope is a prismatic optical system with advantages of clear imaging, multiple working channels and multiple viewpoints. flexible endoscope: A flexible endoscope is an optical-fiber-based system. Notable features of a flexible endoscope include that the lens can be manipulated by the operator to change direction ...
He was the Mallinckrodt Professor of Physics at Harvard University and Adjunct Professor of Optical Sciences at the University of Arizona. Born in New York City, he was awarded one half of the 2005 Nobel Prize in Physics "for his contribution to the quantum theory of optical coherence", with the other half shared by John L. Hall and Theodor W ...