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In the United States military, modafinil has been approved for use on certain Air Force missions, and it is being investigated for other uses. [19] As of November 2012, modafinil is the only drug approved by the Air Force as a "go pill" for fatigue management. [20] The use of dextroamphetamine (a.k.a., Dexedrine) is no longer approved. [20] Yes ...
The US military approved modafinil for specific Air Force missions, replacing amphetamines for fatigue management. [79] The use of modafinil in military contexts without sleep deprivation is not recommended due to inconclusive evidence on its cognitive enhancement benefits and potential risks of adverse effects. [73] Modafinil is also available ...
In contrast to the sleeping agents, a go pill refers to a wakefulness-promoting agent used for fatigue management, especially in a military combat-readiness context; this is contrasted with a no-go pill, which is used to promote sleep in support of combat operations. A go pill generally contains one of the following drugs:
Chemically, flmodafinil is an enantiopure derivative of modafinil and is also known as bisfluoromodafinil (it is the (R)-bis(4-fluoro) phenyl ring-substituted derivative of modafinil). [2] [8] Flmodafinil was developed by NLS Pharma. [3] As of January 2024, it is in preclinical development for treatment of chronic fatigue syndrome. [3]
Approved for treating narcolepsy, obstructive sleep apnea, and shift work sleep disorder, modafinil is a wakefulness-promoting drug used to decrease fatigue, increase vigilance, and reduce daytime sleepiness. [1] Modafinil improves alertness, attention, long-term memory, and daily performance in people with sleep disorders. [1] [18]
This is a complete list of clinically approved prescription antidepressants throughout the world, as well as clinically approved prescription drugs used to augment antidepressants or mood stabilizers, by pharmacological and/or structural classification.
Kash Patel, nominee to be Director of the Federal Bureau of Investigation, testifies in front of the Senate Judiciary Committee in Washington, DC on January 30, 2025.
Management of ME/CFS (myalgic encephalomyelitis/chronic fatigue syndrome) focuses on symptoms management, as no treatments that address the root cause of the illness are available. [ 1 ] : 29 Pacing, or regulating one's activities to avoid triggering worse symptoms, is the most common management strategy for post-exertional malaise .