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A fistula involving the bladder can have one of many specific names, describing the specific location of its outlet: Bladder and intestine: "vesicoenteric", "enterovesical", or "vesicointestinal" [1] [2] [3] Bladder and colon: "vesicocolic" or "colovesical" [4] Bladder and rectum: "vesicorectal" or "rectovesical" [5]
Chlordiazepoxide/clidinium bromide (marketed as Librax) is a fixed-dose combination medication used to treat peptic ulcers, irritable bowel syndrome (IBS), and gastritis. [2] It contains chlordiazepoxide and clidinium bromide. It helps relieve stomach spasms, abdominal cramps, and anxiety related to gastric disorders. [3]
Solabegron (code name GW-427,353) is a drug which acts as a selective agonist for the β 3 adrenergic receptor. It is being developed for the treatment of overactive bladder and irritable bowel syndrome. [1] [2] [3] It has been shown to produce visceral analgesia by releasing somatostatin from adipocytes. [4] [5]
Bladder instillation of medication is one of the main forms of treatment of interstitial cystitis, but evidence for its effectiveness is currently limited. [10] Advantages of this treatment approach include direct contact of the medication with the bladder and low systemic side effects due to poor absorption of the medication. [10]
A study looked at the effects of calcium polycarbophil on general irritable bowel syndrome (IBS) symptoms. Fourteen patients with IBS-diarrhea and twelve with IBS-constipation were given calcium polycarbophil for eight weeks and their colon transit times were measured with radiopaque markers in the colon.
Benefits appear similar to other medications in the class. [4] It is taken by mouth. [1] Common side effects include dry mouth, constipation, and urinary tract infection. [1] [2] Severe side effects may include urinary retention, QT prolongation, hallucinations, glaucoma, and anaphylaxis. [1] [3] [2] It is unclear if use is safe during ...