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  2. Cell isolation - Wikipedia

    en.wikipedia.org/wiki/Cell_isolation

    Cell isolation is the process of separating individual living cells from a solid block of tissue or cell suspension. While some types of cell naturally exist in a separated form (for example blood cells ), other cell types that are found in solid tissue require specific techniques to separate them into individual cells.

  3. Cell-free system - Wikipedia

    en.wikipedia.org/wiki/Cell-free_system

    A cell-free system is an in vitro tool widely used to study biological reactions that happen within cells apart from a full cell system, thus reducing the complex interactions typically found when working in a whole cell. [1]

  4. Single-cell analysis - Wikipedia

    en.wikipedia.org/wiki/Single-cell_analysis

    This single cell shows the process of the central dogma of molecular biology, which are all steps researchers are interested to quantify (DNA, RNA, and Protein).. In cell biology, single-cell analysis and subcellular analysis [1] refer to the study of genomics, transcriptomics, proteomics, metabolomics, and cellcell interactions at the level of an individual cell, as opposed to more ...

  5. Cell culture - Wikipedia

    en.wikipedia.org/wiki/Cell_culture

    Most cells require a surface or an artificial substrate to form an adherent culture as a monolayer (one single-cell thick), whereas others can be grown free floating in a medium as a suspension culture. [2] This is typically facilitated via use of a liquid, semi-solid, or solid growth medium, such as broth or agar.

  6. Single-cell sequencing - Wikipedia

    en.wikipedia.org/wiki/Single-cell_sequencing

    Single-cell DNA genome sequencing involves isolating a single cell, amplifying the whole genome or region of interest, constructing sequencing libraries, and then applying next-generation DNA sequencing (for example Illumina, Ion Torrent). Single-cell DNA sequencing has been widely applied in mammalian systems to study normal physiology and ...

  7. Cell sorting - Wikipedia

    en.wikipedia.org/wiki/Cell_sorting

    Methods of cell sorting fall into two major categories: fluorescence-activated cell sorting (FACS) and immunomagnetic cell sorting. [2] Due to many years of refinement and increased demand for cell separation however, researchers are working to develop microfluidic sorting devices that have many benefits in comparison to the main types of fluorescence-activated cell sorting and immunomagnetic ...

  8. Circulating free DNA - Wikipedia

    en.wikipedia.org/wiki/Circulating_free_DNA

    Cell‐free DNA (cfDNA) is present in the circulating plasma and in other body fluids. [13] The release of cfDNA into the bloodstream appears by different reasons, including apoptosis, necrosis and NETosis. Its rapidly increased accumulation in blood during tumor development is caused by an excessive DNA release by apoptotic cells and necrotic ...

  9. DNA extraction - Wikipedia

    en.wikipedia.org/wiki/DNA_extraction

    The first isolation of deoxyribonucleic acid (DNA) was done in 1869 by Friedrich Miescher. [1] DNA extraction is the process of isolating DNA from the cells of an organism isolated from a sample, typically a biological sample such as blood, saliva, or tissue.