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He was responsible for the development of a whole genome cattle-hamster radiation hybrid (RH) panel. This work fueled a new thrust in cattle genomics and comparative gene mapping. RH mapping is an effective tool for building ordered maps of conserved sequences, derived from genes, thus integrating linkage and physical maps of mammalian chromosomes.
She is also a professor and Canada Research Chair in Livestock Genomics at Ontario Agricultural College at the University of Guelph. [ 2 ] Dr. Christine Baes is a prominent figure in animal science, particularly in the fields of quantitative genetics, genomics, and animal breeding.
The size of the bovine genome is 2.7 Gb (2.7 billion base pairs). [4] It contains approximately 35,092 [4] genes of which 14,000 are common to all mammalian species. Bovines share 80 percent of their genes with humans; cows are less similar to humans than rodents (humans and rodents belong to the clade of Supraprimates) and dogs (humans and dogs belong to the clade of Boreoeutheria).
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In comparative genomics, synteny is the preserved order of genes on chromosomes of related species indicating their descent from a common ancestor.Synteny provides a framework in which the conservation of homologous genes and gene order is identified between genomes of different species. [9]
Animal breeding is a branch of animal science that addresses the evaluation (using best linear unbiased prediction and other methods) of the genetic value (estimated breeding value, EBV) of livestock. Selecting for breeding animals with superior EBV in growth rate, egg, meat, milk, or wool production, or with other desirable traits has ...
Structural genomics seeks to describe the 3-dimensional structure of every protein encoded by a given genome. This genome-based approach allows for a high-throughput method of structure determination by a combination of experimental and modeling approaches .
Computational genomics refers to the use of computational and statistical analysis to decipher biology from genome sequences and related data, [1] including both DNA and RNA sequence as well as other "post-genomic" data (i.e., experimental data obtained with technologies that require the genome sequence, such as genomic DNA microarrays). These ...