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The plague of Justinian or Justinianic plague (AD 541–549) was an epidemic that afflicted the entire Mediterranean Basin, Europe, and the Near East, severely affecting the Sasanian Empire and the Byzantine Empire, especially Constantinople.
The symptoms of bubonic plague are first attested in a fragment of Rufus of Ephesus preserved by Oribasius; these ancient medical authorities suggest bubonic plague had appeared in the Roman Empire before the reign of Trajan, six centuries before arriving at Pelusium in the reign of Justinian I. [41]
The Plague of Justinian in AD 541–542 is the first known attack on record, and marks the first firmly recorded pattern of bubonic plague. This disease is thought to have originated in China. [ 19 ] It then spread to Africa from where the huge city of Constantinople imported massive amounts of grain, mostly from Egypt, to feed its citizens.
Symptoms to watch out for include swollen lymph nodes, sudden fever, head and body aches, weakness, vomiting and nausea, shortness of breath, chest pain, and cough, particularly with bloody mucus ...
Dubbed the Justinian Pandemic or the Plague of Justinian, the disease spread throughout Roman Egypt before infecting the rest of the world over the ensuing 200 years.
Due to the long time spans, the first plague pandemic (6th century – 8th century) and the second plague pandemic (14th century – early 19th century) are shown by individual outbreaks, such as the Plague of Justinian (first pandemic) and the Black Death (second pandemic).
Plague, one of the deadliest bacterial infections in human history, caused an estimated 50 million deaths in Europe during the Middle Ages when it was known as the Black Death.
The first plague pandemic was the first historically recorded Old World pandemic of plague, the contagious disease caused by the bacterium Yersinia pestis. Also called the early medieval pandemic, it began with the Plague of Justinian in 541 and continued until 750 or 767. At least fifteen to eighteen major waves of plague following the ...