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There is ongoing research about the short- and long-term damage COVID-19 may possibly cause to the brain. [ 36 ] including in cases of ' long COVID '. For instance, a study showed how COVID-19 may cause microvascular brain pathology and endothelial cell -death, disrupting the blood–brain barrier .
The main categories linking to the COVID-19 pandemic are: Rapid response, Health System, and Prevention. [34] [35] Despite this assessment, the US failed to prepare critical stockpiles deemed necessary by planning exercises and failed to follow its own planning documents when executing the response to the COVID-19 pandemic. [citation needed]
COVID-19 vaccine clinical research uses clinical research to establish the characteristics of COVID-19 vaccines. These characteristics include efficacy , effectiveness , and safety. As of November 2022 [update] , 40 vaccines are authorized by at least one national regulatory authority for public use: [ 1 ] [ 2 ]
The UNESCO study of publication trends in 193 countries on the topic of new or re-emerging viruses that can infect humans covered the period from 2011 to 2019 and now provides an overview of the state of research prior to the COVID-19 pandemic. Global output on this broad topic increased by only 2% per year between 2011 and 2019, slower than ...
The true COVID-19 death toll in the United States would therefore be higher than official reports, as modeled by a paper published in The Lancet Regional Health – Americas. [3] One way to estimate COVID-19 deaths that includes unconfirmed cases is to use the excess mortality , which is the overall number of deaths that exceed what would ...
In December 2019, a pneumonia outbreak was reported in Wuhan, China. [119] On 31 December 2019, the outbreak was traced to a novel strain of coronavirus, [120] which was given the interim name 2019-nCoV by the World Health Organization, [121] [122] [123] later renamed SARS-CoV-2 by the International Committee on Taxonomy of Viruses.
For the Netherlands, based on overall excess mortality, an estimated 20,000 people died from COVID-19 in 2020, [10] while only the death of 11,525 identified COVID-19 cases was registered. [9] The official count of COVID-19 deaths as of December 2021 is slightly more than 5.4 million, according to World Health Organization's report in May 2022 ...
A COVID-19 vaccine is intended to provide acquired immunity against severe acute respiratory syndrome coronavirus 2 (SARS‑CoV‑2), the virus that causes coronavirus disease 2019 . Prior to the COVID-19 pandemic, an established body of knowledge existed about the structure and function of coronaviruses causing diseases like severe acute ...