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Levodopa-induced dyskinesia (LID) is a form of dyskinesia associated with levodopa (l-DOPA), used to treat Parkinson's disease. It often involves hyperkinetic movements, including chorea, dystonia, and athetosis. [1] In the context of Parkinson's disease (PD), dyskinesia is often the result of long-term dopamine therapy.
Because levodopa bypasses the enzyme tyrosine hydroxylase, the rate-limiting step in dopamine synthesis, it is much more readily converted to dopamine than tyrosine, which is normally the natural precursor for dopamine production. In humans, conversion of levodopa to dopamine does not only occur within the central nervous system.
Selegiline can also cause cardiovascular side effects such as orthostatic hypotension, hypertension, atrial fibrillation, and other types of cardiac arrhythmias. [ 69 ] The main side effects of the patch form for depression include application-site reactions , insomnia , dry mouth , dizziness , nervousness , and abnormal dreams .
Levodopa, a drug used to treat Parkinson’s disease, has been shown to increase the risk for pathological gambling. Patients who receive the drug are also counseled on this potential side effect.
It's very common for weight gain to start during perimenopause, a few years before menopause, per Mayo Clinic. For many women, this can start in their 40s, and weight gain often continues at about ...
This is because muscle loss is common among people on a weight loss journey—and protein is the building block of muscle. But this doesn’t mean you need to be drinking protein shakes all day ...
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