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Oxamate is the carboxylate anion of oxamic acid. [1] Oxamate has a molecular formula of C 2 H 2 NO 3 − and is an isosteric form of pyruvate. Salts and esters of oxamic acid are known collectively as oxamates. Oxamate is a competitive inhibitor of the enzyme lactate dehydrogenase. [2]
Metadoxine is an ion pair salt of pyridoxine and pyrrolidone carboxylate (PCA). [1] Pyridoxine (vitamin B 6 ) is a precursor of coenzymes including pyridoxal 5’-phosphate (PLP), which accelerates the metabolic degradation of ethanol and prevents adenosine triphosphate (ATP) inactivation by acetaldehyde .
An ester of a carboxylic acid.R stands for any group (typically hydrogen or organyl) and R ′ stands for any organyl group.. In chemistry, an ester is a compound derived from an acid (organic or inorganic) in which the hydrogen atom (H) of at least one acidic hydroxyl group (−OH) of that acid is replaced by an organyl group (R ′). [1]
The sodium salt of phenylacetic acid, sodium phenylacetate, is used as a pharmaceutical drug for the treatment of urea cycle disorders, including as the combination drug sodium phenylacetate/sodium benzoate (Ammonul). [8]
Polystyrene sulfonates can bind to various drugs within the digestive tract and thus lower their absorption and effectiveness. Common examples include lithium, thyroxine, and digitalis. In September 2017, the FDA recommended separating the dosing of polystyrene sulfonate from any other oral medications by at least three hours to avoid any ...
Carboxylate ion Acrylate ion. In organic chemistry, a carboxylate is the conjugate base of a carboxylic acid, RCOO − (or RCO − 2). It is an anion, an ion with negative charge. Carboxylate salts are salts that have the general formula M(RCOO) n, where M is a metal and n is 1, 2,....
Two popular drugs, often called alkanolamine beta blockers, are members of this structural class: propranolol, pindolol. Isoetarine is yet another medicinally useful derivative of ethanolamine. [citation needed]
Piperine forms salts only with strong acids. The platinichloride B 4 ·H 2 PtCl 6 forms orange-red needles ("B" denotes one mole of the alkaloid base in this and the following formula). Iodine in potassium iodide added to an alcoholic solution of the base in the presence of a little hydrochloric acid gives a characteristic periodide, B 2 ·HI ...