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Serious side effects may include psychosis, increased risk of infections, adrenal suppression, and bronchospasm. [6] Use in pregnancy is generally safe. [7] It works by decreasing inflammation and immune system activity. [6] Triamcinolone was patented in 1956 and came into medical use in 1958. [8] It is available as a generic medication. [9]
Eplerenone may have a lower incidence than spironolactone of sexual side effects such as feminization, gynecomastia, impotence, low sex drive and reduction of size of male genitalia. [18] This is because other antimineralocorticoids have structural elements of the progesterone molecule, causing progestogenic and antiandrogenic outcomes. [ 4 ]
Triamcinolone commonly cause local side effects only. The undesirable effects may be oral mucosa changes that breaks the inner mouth mucosal layer. The damage in the mucosa may also cause redness and irritation on the application area. [4] In rare situations, systemic side effects may occur.
In general, use a potent preparation short term and weaker preparation for maintenance between flare-ups. While there is no proven best benefit-to-risk ratio, [11] if prolonged use of a topical steroid on a skin surface is required, a pulse therapy should be undertaken.
Eplerenone is a newer drug that was developed as a spironolactone analog with reduced adverse effects. In addition to the y-lactone ring and the substituent on C-7, eplerenone has a 9α,11α-epoxy group. This group is believed to be the reason why eplerenone has a 20-40-fold lower affinity for the mineralocorticoid receptor than spironolactone. [7]
A study confirmed that side effects like pancreatitis and kidney damage are possible while taking GLP-1s like Ozempic. Here's what a doctor wants you to know.
Other side effects that have received a lot of attention lately are “Ozempic face,” and “Ozempic butt.” Ozempic face is a sagging of the skin that occurs because of weight loss.
Bryan Johnson, known for spending $2M annually to reverse his body’s aging process, stopped taking a drug that had been tested on mice after experiencing severe side effects. The businessman had ...