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Dibenzazepine (iminostilbene) is a chemical compound with two benzene rings fused to an azepine ring. [1] Many pharmaceuticals, such as carbamazepine , oxcarbazepine , and depramine , are based on a dibenzazepine structure.
Dibenzepin, sold under the brand name Noveril among others, is a tricyclic antidepressant (TCA) used widely throughout Europe for the treatment of depression. [ 2 ] [ 3 ] [ 4 ] It has similar efficacy and effects relative to other TCAs like imipramine but with fewer side effects .
Historically, "conventional" pharmacotherapy has been used to reduce behaviors and sensitivities associated with ASD. [13] Many such treatments have been prescribed off-label in order to target specific symptoms. [14] Today, medications are primarily prescribed to adults with autism to avoid any adverse effects in the developing brains of children.
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PDD-NOS is not a current part of the Diagnostic and Statistical Manual of Mental Disorders typology (as of the DSM-5), which is the most common diagnostic typology used in the United States. In the still used (though deprecated) ICD-10, it is considered "atypical autism" and "pervasive developmental disorder, unspecified". [8]
The first four of these disorders are commonly called the autism spectrum disorders; the last disorder is much rarer, and is sometimes placed in the autism spectrum and sometimes not. [2] [3] There is a division among doctors on the use of the term PDD. [4] Many use the term PDD as a short way of saying PDD-NOS. [4]
Used to treat psychotic disorders including schizophrenia, acute manic episodes, and maintenance of bipolar disorder. Used as an adjunct to antidepressant therapy, either alone or in combination with fluoxetine as Symbyax. Quetiapine (Seroquel) – Of the dibenzothiazepine class of atypical antipsychotics. Used primarily to treat bipolar ...
[24] [25] The ADI-R is a semi-structured parent interview that probes for symptoms of autism by evaluating a child's current behavior and developmental history. The ADOS is a semi-structured interactive evaluation of ASD symptoms that is used to measure social and communication abilities by eliciting several opportunities for spontaneous ...