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Sequential analysis also has a connection to the problem of gambler's ruin that has been studied by, among others, Huygens in 1657. [12]Step detection is the process of finding abrupt changes in the mean level of a time series or signal.
A cross-sequential design is a research method that combines both a longitudinal design and a cross-sectional design. It aims to correct for some of the problems inherent in the cross-sectional and longitudinal designs.
The use of a sequence of experiments, where the design of each may depend on the results of previous experiments, including the possible decision to stop experimenting, is within the scope of sequential analysis, a field that was pioneered [12] by Abraham Wald in the context of sequential tests of statistical hypotheses. [13]
[18] [19] [20] The study of interaction patterns is increasingly centered on sequential concepts, such as turn-taking, the predominance of reciprocal utterances, and the strategic solicitation of preferred types of responses (see Conversation Analysis).
A research design typically outlines the theories and models underlying a project; the research question(s) of a project; a strategy for gathering data and information; and a strategy for producing answers from the data. [1] A strong research design yields valid answers to research questions while weak designs yield unreliable, imprecise or ...
For trials with a binary (response/no response) outcome and a single treatment arm, a popular and simple group sequential design with two stages is the Simon design. In this design, there is a single interim analysis partway through the trial, at which point the trial either stops for futility or continues to the second stage. [22]
Repeated measures design is a research design that involves multiple measures of the same variable taken on the same or matched subjects either under different conditions or over two or more time periods. [1] For instance, repeated measurements are collected in a longitudinal study in which change over time is assessed.
In medicine, a crossover study or crossover trial is a longitudinal study in which subjects receive a sequence of different treatments (or exposures). While crossover studies can be observational studies , many important crossover studies are controlled experiments , which are discussed in this article.