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It is commonly available without a prescription in various dosage forms, such as a topical cream, ointment, or vaginal suppository. [2] [7] It is also available as an oral troche or throat lozenge as a prescription only. Topically, clotrimazole is used for vulvovaginal candidiasis (yeast infection) or yeast infections of the skin. For ...
A one-time dose of fluconazole by mouth is 90% effective in treating a vaginal yeast infection. [70] For severe nonrecurring cases, several doses of fluconazole is recommended. [20] Local treatment may include vaginal suppositories or medicated douches. Other types of yeast infections require different dosing.
Fluconazole was patented in 1981 and came into commercial use in 1988. [7] It is on the World Health Organization's List of Essential Medicines. [8] Fluconazole is available as a generic medication. [5] In 2022, it was the 160th most commonly prescribed medication in the United States, with more than 3 million prescriptions. [9] [10]
This is particularly true when it comes to urinary tract infections and yeast infections, two of the most common to afflict women — about 50% to 60% will experience a UTI at least once in her ...
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However, ketoconazole has largely been replaced as a first-line systemic antifungal medication by other azole antifungal agents, such as fluconazole and/or itraconazole, because of ketoconazole's greater toxicity, poorer absorption, and more limited spectrum of activity. [23] [24]