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Epoxy resins derived from bisphenol A are used as coatings on the inside of almost all food and beverage cans; [13] however, due to BPA health concerns, in Japan epoxy coating was mostly replaced by PET film. [14] Bisphenol A is a preferred color developer in carbonless copy paper and thermal point of sale receipt paper.
Bisphenol A (BPA) is a chemical compound primarily used in the manufacturing of various plastics. It is a colourless solid which is soluble in most common organic solvents , but has very poor solubility in water.
4-Methyl-2,4-bis(4-hydroxyphenyl)pent-1-ene (MBP) is a metabolite of bisphenol A (BPA). [1] MBP has potent estrogenic activity in vitro and in vivo , up to thousandfold stronger than BPA. [ 2 ] It may also play a role in neuronal cell apoptosis [ 3 ] and may increase risk for several forms of cancer.
Exceptions include bisphenol S, P, and M. "Bisphenol" is a common name; the letter following denotes the variant, which depends on the additional substituents. Bisphenol A is the most popular representative of the group, with millions of metric tons produced globally in the past decade, often simply called "bisphenol".
Bisphenol A diglycidyl ether slowly hydrolyzes to 2,2-bis[4(2,3-dihydroxypropoxy)phenyl)propane (bis-HPPP). Similarly, DGEBA reacts with acrylic acid to give vinyl ester resins . The reaction results in opening of the epoxide ring, generating unsaturated esters at each terminus of the molecule.
Bis-GMA (bisphenol A-glycidyl methacrylate) is a resin commonly used in dental composite, dental sealants. [1] [2] and dental cement. It is the diester derived from methacrylic acid and the bisphenol A diglycidyl ether. Bearing two polymerizable groups, it is prone to form a crosslinked polymer that is used in dental restorations. [3]
Safe treatment shows Alzheimer’s potential. One of the challenges of treating Alzheimer’s is finding therapeutics that can cross the blood-brain barrier and get into the brain. Xenon gas can ...
It has been proposed that dinitrobisphenol A might be formed in vivo by peroxynitrite mediated oxidations of bisphenol A and that it may exhibit higher toxicity than BPA itself. [ 3 ] 3,3'-Dinitrobisphenol A is found to be genotoxic in male ICR mice on a micronucleus test. [ 4 ]