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Brevetoxin (PbTx), or brevetoxins, are a suite of cyclic polyether compounds produced naturally by a species of dinoflagellate known as Karenia brevis.Brevetoxins are neurotoxins that bind to voltage-gated sodium channels in nerve cells, leading to disruption of normal neurological processes and causing the illness clinically described as neurotoxic shellfish poisoning (NSP). [1]
Neosaxitoxin (NSTX) is included, as other saxitoxin-analogs, in a broad group of natural neurotoxic alkaloids, commonly known as the paralytic shellfish toxins (PSTs).The parent compound of PSTs, saxitoxin (STX), is a tricyclic perhydropurine alkaloid, which can be substituted at various positions, leading to more than 30 naturally occurring STX analogues.
Saxitoxin is a neurotoxin naturally produced by certain species of marine dinoflagellates (Alexandrium sp., Gymnodinium sp., Pyrodinium sp.) and freshwater cyanobacteria (Dolichospermum cicinale sp., some Aphanizomenon spp., Cylindrospermopsis sp., Lyngbya sp., Planktothrix sp.) [1] [2] Saxitoxin accumulates in "planktivorous invertebrates, including mollusks (bivalves and gastropods ...
Other potential causes such as paralytic shellfish poisoning (PSP), neurotoxic shellfish poisoning (NSP), scombrotoxin fish poisoning, and pufferfish poisoning should be excluded. [1] The reversal of hot and cold sensations is an occasional symptom of CFP that may help differentiate it from norovirus. [20]
Paralytic shellfish poisoning, or PSP, is caused by saxitoxin, a naturally occurring toxin that’s produced by algae. Saxitoxin is a neurotoxin, meaning it can damage nerve tissue.
PSP affects those who come into contact with the affected shellfish by ingestion. [1] The toxins responsible for most shellfish poisonings—mainly saxitoxin, although several other toxins have been found, such as neosaxitoxin and gonyautoxins I to IV—are water-insoluble, and heat- and acid-stable. Therefore, ordinary cooking methods will not ...
Paralytic shellfish poisoning, or PSP, happens after consuming shellfish contaminated with saxitoxin, which can cause gastrointestinal distress, neurological symptoms, and a sensation of ...
The oysters and bay clams involved in the warning were harvested from certain growing areas in Oregon and Washington.