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BALB/c is an albino, laboratory-bred strain of the house mouse from which a number of common substrains are derived. Now over 200 generations from New York in 1920, BALB/c mice are distributed globally, and are among the most widely used inbred strains used in animal experimentation.
BALB/c laboratory mice BALB/c is an albino laboratory-bred strain from which a number of common substrains are derived. With over 200 generations bred since 1920, BALB/c mice are distributed globally and are among the most widely used inbred strains used in animal experimentation .
Nude mice were the earliest immunodeficient mouse model. These mice primarily produced IgM and had minimal or no IgA. As a result, they did not exhibit a rejection response to allogeneic tissue. Commonly utilized strains included BALB/c-nu, Swiss-nu, NC-nu, and NIH-nu, which were extensively employed in the research of immune diseases and tumors.
Eesti: Täiskasvanud Balb/C paljad hiired (nude mice), kellel puudub tüümus, mistõttu neil puuduvad ka T-lümfotsüüdid ja esineb immuunpuudulikkus. English: Balb/C nude mice, the animals lacks a thymus and they are unable to produce T cells , and are therefore immunodeficient .
4T1 is a breast cancer cell line derived from the mammary gland tissue of a mouse BALB/c strain. [ 1 ] 4T1 cells are epithelial and are resistant to 6-thioguanine . [ 1 ] In preclinical research, 4T1 cells have been used to study breast cancer metastasis as they can metastasize to the lung, liver, lymph nodes, brain and bone.
It is the most widely used "genetic background" for genetically modified mice for use as models of human disease. They are the most widely used and best-selling mouse strain due to the availability of congenic strains, easy breeding, and robustness. [1] The median lifespan of C57BL/6 mice is 27–29 months and the maximum lifespan is about 36 ...
A nude mouse. A nude mouse is a laboratory mouse from a strain with a genetic mutation that causes a deteriorated or absent thymus, resulting in an inhibited immune system due to a greatly reduced number of T cells.
Download as PDF; Printable version; In other projects Wikidata item; Appearance. ... Mice is the plural form of mouse, a rodent. Mice or MICE may also refer to: Acronyms