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Ghrelin cells are found mainly in the stomach [24] and duodenum, but also in the jejunum, lungs, pancreatic islets, [25] gonads, adrenal cortex, placenta, and kidney. It has also been shown that ghrelin is produced locally in the brain. [26] Additionally, research suggests that ghrelin may be produced in the myocardium and have an 'autocrine ...
Ghrelin is a peptide hormone released from the stomach and liver and is often referred to as the "hunger hormone" since high levels of it are found in individuals that are fasting. Ghrelin agonistic treatments can be used to treat illnesses such as anorexia and loss of appetites in cancer patients.
The kidneys have two cells that help to maintain acid-base homeostasis: intercalated A and B cells. The intercalated A cells are stimulated when the body is experiencing acidic conditions. Under acidic conditions, the high concentration of CO 2 in the blood creates a gradient for CO 2 to move into the cell and push the reaction HCO 3 + H ↔ H ...
The juxtaglomerular apparatus (also known as the juxtaglomerular complex) is a structure in the kidney that regulates the function of each nephron, the functional units of the kidney. The juxtaglomerular apparatus is named because it is next to (juxta-[1]) the glomerulus. The juxtaglomerular apparatus consists of three types of cells:
Mesangial cells are modified smooth muscle cells that lie between the capillaries. They regulate blood flow by their contractile activity and secrete extracellular matrix, prostaglandins, and cytokines. Mesangial cells also have phagocytic activity, removing proteins and other molecules trapped in the glomerular basement membrane or filtration ...
People with type 2 diabetes and obesity who develop kidney disease may benefit more from bariatric surgery than from GLP-1 drugs when it comes to preserving kidney function, a new study finds.
The capsule and tubule are connected and are composed of epithelial cells with a lumen. A healthy adult has 1 to 1.5 million nephrons in each kidney. [1]: 22 Blood is filtered as it passes through three layers: the endothelial cells of the capillary wall, its basement membrane, and between the podocyte foot processes of
Mesangial cells are specialised cells in the kidney that make up the mesangium of the glomerulus. Together with the mesangial matrix, they form the vascular pole of the renal corpuscle . [ 1 ] The mesangial cell population accounts for approximately 30-40% of the total cells in the glomerulus. [ 2 ]
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