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SAFE Hi-C was successfully used to generate an amplification-free, in situ Hi-C ligation library from as low as 250 thousand K562 cells. [17] Ligation fragments are anywhere between 200 and 500 bp long, with an average at about 370 bp. [17] All ligation product libraries were sequenced using the Illumina HiSeq platform (2x150 bp paired-end ...
In 2013, Takashi Nagano and Peter Fraser introduced in-nuclei ligation for Hi-C and single-cell Hi-C. [26] In 2014, Suhas Rao, Miriam Huntley, et al. developed in-situ Hi-C and the use of 4-cutter restriction enzymes, and released the first high-resolution datasets down to kilobase resolution for several human cell lines.
Hydrophilic interaction chromatography (or hydrophilic interaction liquid chromatography, HILIC) [1] is a variant of normal phase liquid chromatography that partly overlaps with other chromatographic applications such as ion chromatography and reversed phase liquid chromatography.
When you think of free games to play on PC it's easy to think of flash gaming sites or Facebook games, which are perfectly acceptable forms of casual gaming, but what if you want a more ...
Check out the best free online games of 2013! 10. Diner Dash: Hometown Hero On a visit to her hometown, Flo and her Grandma Florence take a stroll down memory lane. Bring five restaurants back to ...
Microsoft offers free 90-day trials for every variety of its Office Suite, from Professional to Student. After your 90 days are up, the software will be locked until you provide a valid code ...
A humidity indicator card (HIC) is a card on which a moisture-sensitive chemical is impregnated such that it will change color when the indicated relative humidity (RH) is exceeded. This has usually been a blotting paper impregnated with cobalt(II) chloride base; Less toxic alternatives include other chemicals such as cobalt-free chloride base ...
An (orange-epoxy) encapsulated hybrid circuit on a printed circuit board (PCB).. A hybrid integrated circuit (HIC), hybrid microcircuit, hybrid circuit or simply hybrid is a miniaturized electronic circuit constructed of individual devices, such as semiconductor devices (e.g. transistors, diodes or monolithic ICs) and passive components (e.g. resistors, inductors, transformers, and capacitors ...