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Like modafinil, armodafinil is an inhibitor and/or inducer of certain cytochrome P450 enzymes. [7] [26] It moderately induces CYP3A4 and moderately inhibits CYP2C19. [7] [26] In contrast to modafinil however, armodafinil does not induce CYP1A2. [7] [26]
Armodafinil; Barbiturates (e.g., butalbital, ... Long List of Inhibitors and Inducers of CYP3A4 and CYP2D6". ... This page was last edited on 1 November 2024, ...
Adrafinil, sold under the brand name Olmifon, is a wakefulness-promoting medication that was formerly used in France to improve alertness, attention, wakefulness, and mood, particularly in the elderly.
Chemical structure of modafinil.. This page lists chemical compounds similar to modafinil, known as modafinil analogues and derivatives.These are structural analogues and derivatives of modafinil, a drug that affects dopamine levels in the brain in an unusual way (atypical dopamine reuptake inhibitor or DRI).
How long does COVID-19 last? Depending on whether you’ve experienced a mild or severe case of COVID-19, recovery times will vary. When it comes to mild cases of COVID-19, “in general, we would ...
The long-term safety and effectiveness of modafinil have not been conclusively established. [100] The FDA does not endorse modafinil for children's medical conditions due to an increased risk of rare but serious dermatological toxicity, manifested as Stevens–Johnson syndrome which is a type of severe skin reaction.
[2] [8] Unlike modafinil, flmodafinil does not induce cytochrome P450 enzymes. [2] Chemically, flmodafinil is an enantiopure derivative of modafinil and is also known as bisfluoromodafinil (it is the (R)-bis(4-fluoro) phenyl ring-substituted derivative of modafinil). [2] [8] Flmodafinil was developed by NLS Pharma. [3]
A high-fat meal has minimal influence on the peak and total concentrations of solriamfetol, but does delay time to peak levels by approximately 1 hour. [1] The apparent volume of distribution of solriamfetol is approximately 199 L. [1] The plasma protein binding of solriamfetol is 13.3% to 19.4% over a concentration range of 0.059 to 10.1 μg ...