Search results
Results From The WOW.Com Content Network
The following other wikis use this file: Usage on ar.wikipedia.org بريدنيزولون; Usage on azb.wikipedia.org پردنیزولون; Usage on de.wikipedia.org
Main page; Contents; Current events; Random article; About Wikipedia; Contact us; Donate
Prednisone is a prodrug and must be converted to prednisolone by the liver before it becomes active. [6] [7] Prednisolone then binds to glucocorticoid receptors, activating them and triggering changes in gene expression. [4] Prednisone was patented in 1954 and approved for medical use in the United States in 1955.
Main page; Contents; Current events; Random article; About Wikipedia; Contact us; Pages for logged out editors learn more
Prednisolone has a relatively short half-life, ranging 2–4 hours. It also has a large therapeutic window, considering the dosage required to produce a therapeutic effect is a few times higher than what the body naturally produces. [14] Prednisolone is 70–90% plasma protein bound, it binds to proteins such as albumin. [14]
Prednisolone acetate is acutely toxic with an LD50 of >240 mg/kg for a rat and 3500 mg/kg for a mouse. Effects may present delayed. Target organs include adrenal cortex, bones, and eyes. It is also a known teratogen. [3] Class B PPE should be worn when working with this chemical. Any contact with this chemical should be taken seriously and the ...
Prednisolone sodium phosphate is a synthetic glucocorticoid corticosteroid and a corticosteroid ester. References. External links "Prednisolone sodium phosphate ...
Δ 7-Prednisolone, or 7-dehydroprednisolone, is a synthetic glucocorticoid corticosteroid which was never marketed. [1] [2] [3] References This page was last edited ...