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The confidence interval can be expressed in terms of probability with respect to a single theoretical (yet to be realized) sample: "There is a 95% probability that the 95% confidence interval calculated from a given future sample will cover the true value of the population parameter."
Fieller showed that if a and b are (possibly correlated) means of two samples with expectations and , and variances and and covariance , and if ,, are all known, then a (1 − α) confidence interval (m L, m U) for / is given by
In contrast, it is worth noting that other confidence interval may have coverage levels that are lower than the nominal , i.e., the normal approximation (or "standard") interval, Wilson interval, [8] Agresti–Coull interval, [13] etc., with a nominal coverage of 95% may in fact cover less than 95%, [4] even for large sample sizes.
In the social sciences, a result may be considered statistically significant if its confidence level is of the order of a two-sigma effect (95%), while in particle physics and astrophysics, there is a convention of requiring statistical significance of a five-sigma effect (99.99994% confidence) to qualify as a discovery.
For instance, if estimating the effect of a drug on blood pressure with a 95% confidence interval that is six units wide, and the known standard deviation of blood pressure in the population is 15, the required sample size would be =, which would be rounded up to 97, since sample sizes must be integers and must meet or exceed the calculated ...
Confidence intervals are used to estimate the parameter of interest from a sampled data set, commonly the mean or standard deviation. A confidence interval states there is a 100γ% confidence that the parameter of interest is within a lower and upper bound.
For a confidence level, there is a corresponding confidence interval about the mean , that is, the interval [, +] within which values of should fall with probability . Precise values of z γ {\displaystyle z_{\gamma }} are given by the quantile function of the normal distribution (which the 68–95–99.7 rule approximates).
In statistical prediction, the coverage probability is the probability that a prediction interval will include an out-of-sample value of the random variable. The coverage probability can be defined as the proportion of instances where the interval surrounds an out-of-sample value as assessed by long-run frequency. [2]