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In cells of the kidney, cyclooxygenases catalyse the conversion of paracetamol into N-acetyl-p-benzoquinoneimine (NAPQI). [15] NAPQI depletes glutathione via non-enzymatic conjugation with glutathione, a naturally occurring antioxidant. [16] With depletion of glutathione, cells of the kidney become particularly sensitive to oxidative damage.
Glutathione (GSH, / ˌ ɡ l uː t ə ˈ θ aɪ oʊ n /) is an organic compound with the chemical formula HOCOCH(NH 2)CH 2 CH 2 CONHCH(CH 2 SH)CONHCH 2 COOH. It is an antioxidant in plants , animals , fungi , and some bacteria and archaea .
Glutathione is also linked to the newly popular NAC, or N-acetyl cysteine supplements. As of late, NAC supplements have become the elixir du jour. Of course, no one supplement is a cure-all, but ...
Plus, glutathione side effects and dosages. Here, find the health benefits of glutathione, an antioxidant that helps make proteins in the body. Plus, glutathione side effects and dosages.
Kidneys are important for regulating blood pressure and filtering waste products from the bloodstream; managing urine excretion to prevent dehydration; and regulating levels of electrolytes and ...
14858 Ensembl ENSG00000243955 ENSMUSG00000057933 UniProt P08263 P10648 RefSeq (mRNA) NM_145740 NM_001319059 NM_008182 RefSeq (protein) NP_001305988 NP_665683 NP_032208 Location (UCSC) Chr 6: 52.79 – 52.8 Mb Chr 9: 78.24 – 78.26 Mb PubMed search Wikidata View/Edit Human View/Edit Mouse Glutathione S-transferase A1 is an enzyme that in humans is encoded by the GSTA1 gene. Cytosolic and ...