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Stiff-person syndrome (SPS), also known as stiff-man syndrome, [1] is a rare neurological disorder of unclear cause characterized by progressive muscular rigidity and stiffness. The stiffness primarily affects the truncal muscles and is characterised by spasms , resulting in postural deformities.
They can start and stop abruptly, typically waning in strength and are unaffected by voluntary activity. [3] The symptoms (especially the stiffness and fasciculations) are most prominent in the calves, legs, trunk, and sometimes the face and neck, but can also affect other body parts. NMT symptoms may fluctuate in severity and frequency.
Heavy legs is a condition described as an unpleasant sensation of pain and heaviness in the lower limbs. Symptoms include legs feeling weighted, stiff, and tired. Heavy legs can be caused by a wide-ranging collection of disorders including but not restricted to varicose veins, peripheral artery disease, restless legs syndrome, multiple sclerosis, venous insufficiency.
Rigid spine syndrome, also known as congenital muscular dystrophy with rigidity of the spine (CMARS), is a rare and often debilitating neuromuscular disorder.It is characterized by progressive muscle stiffness and rigidity, particularly in the spine, which can severely limit mobility and impact quality of life.
Here you can see a typical test where the first lactate threshold is at around 210-215 power output and their second lactate threshold is at 260-265.
Painful legs (or arms), moving toes (or fingers) syndrome G25.81 Sporadic restless leg syndrome: G25.82 Familial restless leg syndrome G25.83 Stiff-person syndrome: 333.91 G25.84 Ballismus (violent involuntary rapid and irregular movements) G25.85 Hemiballismus (affecting only one side of the body) G25.85 Myokymia, facial G51.4
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Seven years later, John Marshall is still suffering from chronic pain and regular muscle spasms.