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"The dose makes the poison" (Latin: dosis sola facit venenum 'only the dose makes the poison') is an adage intended to indicate a basic principle of toxicology. It is credited to Paracelsus who expressed the classic toxicology maxim "All things are poison, and nothing is without poison; the dosage alone makes it so a thing is not a poison."
Immunity is generally only possible with biologically complex types which the immune system can respond to. Depending on the toxin, the practice can lead to the lethal accumulation of a poison in the body. Results depend on how each poison is processed by the body, i.e. on how the toxic compound is metabolized or passed out of the body. [8]
Paracelsus was born in Egg an der Sihl [], [18] a village close to the Etzel Pass in Einsiedeln, Schwyz.He was born in a house next to a bridge across the Sihl river.His father Wilhelm (d. 1534) was a chemist and physician, an illegitimate descendant of the Swabian noble Georg [] Bombast von Hohenheim (1453–1499), commander of the Order of Saint John in Rohrdorf.
A description of a chemical’s toxic effects, without an understanding the dose to which one might be exposed, is not helpful. Michael Dourson: It is the dose that makes the poison Skip to main ...
In the King James Version of the Bible the text reads: 17 Even so every good tree bringeth forth good fruit; but a corrupt tree bringeth forth evil fruit. 18 A good tree cannot bring forth evil fruit, neither can a corrupt tree bring forth good fruit. The World English Bible translates the passage as: 17 Even so, every good tree produces good ...
It's just as if a man were wounded with an arrow thickly smeared with poison. His friends & companions, kinsmen & relatives would provide him with a surgeon, and the man would say, 'I won't have this arrow removed until I know whether the man who wounded me was a noble warrior, a priest, a merchant, or a worker.'
Bacteria are for example a common adversary for Penicillium chrysogenum mold and humans, and since the mold's poison only targets bacteria, humans use it for getting rid of it in their bodies. Human antimicrobial peptides which are toxic to viruses, fungi, bacteria, and cancerous cells are considered a part of the immune system. [4]
Even during food processing, there are several procedures that strip foods of their poisons to make them human-friendly. Check out the slideshow above to learn what common edible contains cyanide ...