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This is known as Magnetic Resonance guided Focused Ultrasound (MRgFUS) or High Intensity Focused Ultrasound (HIFU). These procedures generally use lower frequencies than medical diagnostic ultrasound (from 0.7 to 2 MHz), but higher the frequency means lower the focusing energy. HIFU treatment is often guided by MRI.
Ultrasonic sonicators generate ultrasound waves, which is a longitudinal compression wave, by converting electrical energy into mechanical energy by deformation of piezoelectric crystals in response to an electric field. [1] [3] The frequency of the waves generated by this method can range from 20 kHz up to 3 MHz. [3]
The ultrasound within tissue consists of very high frequency sound waves, between 800,000 Hz and 20,000,000 Hz, which cannot be heard by humans. Some of the advantages of ultrasound as a diagnostic and therapeutic tool include its safety profile, lack of radiation, portability, and low cost. [ 4 ]
An ultrasonic examination. Ultrasound is sound with frequencies greater than 20 kilohertz. [1] This frequency is the approximate upper audible limit of human hearing in healthy young adults. The physical principles of acoustic waves apply to any frequency range, including ultrasound.
Photoacoustic imaging or optoacoustic imaging is a biomedical imaging modality based on the photoacoustic effect.Non-ionizing laser pulses are delivered into biological tissues and part of the energy will be absorbed and converted into heat, leading to transient thermoelastic expansion and thus wideband (i.e. MHz) ultrasonic emission.
Medical ultrasound includes diagnostic techniques (mainly imaging techniques) using ultrasound, as well as therapeutic applications of ultrasound. In diagnosis, it is used to create an image of internal body structures such as tendons, muscles, joints, blood vessels, and internal organs, to measure some characteristics (e.g., distances and velocities) or to generate an informative audible sound.
The ultrasound probe emits a high-frequency sound wave (usually a multiple of 2 MHz) that bounces off various substances in the body. These echoes are detected by a sensor in the probe. In the case of blood in an artery , the echoes have different frequencies depending on the direction and speed of the blood because of the Doppler effect . [ 2 ]
Ultrasound imaging deposits energy over a large area while therapeutic ultrasound focuses the energy on one target site. Focused ultrasound for intracrainial drug delivery is a non-invasive technique that uses high-frequency sound waves (focused ultrasound, or FUS) to disrupt tight junctions in the blood–brain barrier (BBB), allowing for increased passage of therapeutics into the brain.