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The virions are about 75 nm wide and 180 nm long. [2] Rhabdoviruses are enveloped and have helical nucleocapsids and their genomes are linear, around 11–15 kb in length. [5] [2] Rhabdoviruses carry their genetic material in the form of negative-sense single-stranded RNA.
Rhabdomyolysis (shortened as rhabdo) is a condition in which damaged skeletal muscle breaks down rapidly, often due to high intensity exercise over a short period. [ 6 ] [ 4 ] [ 5 ] Symptoms may include muscle pains , weakness, vomiting , and confusion .
These systemic effects are caused by a traumatic rhabdomyolysis. As muscle cells die, they absorb sodium, water, and calcium; the rhabdomyolysis releases potassium, myoglobin, phosphate, thromboplastin, creatine, and creatine kinase. [citation needed] Crush syndrome can directly come from compartment syndrome, if the injury is left untreated. [8]
Rhabdo symptoms can appear any time after a muscle injury, and for some start several days later. You might have one or more of these symptoms if you develop rhabdo, in which case you should ...
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Treatment for metastatic rhabdomyosarcoma has not changed over the last three decades and five-year survival outcomes in those with high-risk rhabdomyosarcoma remain less than 40%. [37] In terms of overall survival, metastatic rhabdomyosarcoma remains at 21% while recurrent rhabdomyosarcoma remains at 30%. [32]
It is most commonly associated with the tongue, [3] and heart, [4] but can also occur in other locations, such as the vagina. [5] Malignant skeletal muscle tumors are referred to as rhabdomyosarcoma. Only rare cases of possible malignant change have been reported in fetal rhabdomyoma.
RMS can occur in almost any soft-tissue site in the body; the most common primary sites are genitourinary (24%), parameningeal (16%), extremity (19%), orbit (9%), other head and neck (10%), and miscellaneous other sites (22%). [14] RMS often presents as a mass, but signs and symptoms can vary widely depending on the site of the primary tumor.