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Effective treatment against all stages of the disease may require a combination of medications. [2] Infections without symptoms may be treated with just one antibiotic, and infections with symptoms are treated with two antibiotics. [3] Amoebiasis is present all over the world, [6] though most cases occur in the developing world. [7]
Paromomycin is an antimicrobial used to treat a number of parasitic infections including amebiasis, giardiasis, leishmaniasis, and tapeworm infection. [3] It is a first-line treatment for amebiasis or giardiasis during pregnancy. [3] Otherwise, it is generally a second line treatment option. [3]
Poor sanitary conditions are known to increase the risk of contracting amebiasis E. histolytica. [11] In the United States, there is a much higher rate of amebiasis-related mortality in California and Texas (this might be caused by the proximity of those states to E. histolytica-endemic areas, such as Mexico), parts of Latin America, and Asia. [12]
Carbarsone is an organoarsenic compound used as an antiprotozoal drug for treatment of amebiasis and other infections. [1] [2] [3] It was available for amebiasis in the United States as late as 1991.
In addition to the tissue amebicides above, one of the following lumenal amebicides should be prescribed as an adjunctive treatment, either concurrently or sequentially, to destroy E. histolytica in the colon: Paromomycin 500 mg three times a day for 10 days; Iodoquinol 650 mg three times a day for 20 days
With correct treatment, most cases of amoebic and bacterial dysentery subside within 10 days, and most individuals achieve a full recovery within two to four weeks after beginning proper treatment. If the disease is left untreated, the prognosis varies with the immune status of the individual patient and the severity of disease.
In ocular rosacea, treatment period is 2 to 3 months. After discontinuation of doxycycline, recurrences may occur within three months; therefore, many studies recommend either slow tapering or treatment with a lower dose over a longer period of time. [43] Doxycycline is used as an adjunctive therapy for acute intestinal amebiasis. [44]
Chloroquine is also occasionally used for amebiasis that is ... the National Institutes of Health issued treatment guidelines recommending against the use of ...