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Pyelonephritis is inflammation of the kidney, typically due to a bacterial infection. [3] Symptoms most often include fever and flank tenderness . [ 2 ] Other symptoms may include nausea , burning with urination , and frequent urination . [ 2 ]
The CVA is an anatomic concept of the relationship of the 12th rib to the transverse processes of the lumbar vertebrae. [1] There is one CVA on each side of the spine. [2] The lateral part of the CVA is formed by the lower border of the 12th rib, and the medial part of the CVA is formed by the transverse processes of the lumbar vertebrae. [1]
Lloyd's sign indicates the presence of renal calculus or pyelonephritis when pain is elicited by deep percussion in the back between the 12th rib and the spine. [1] It is closely related to costovertebral angle tenderness, as the area of percussion is the same. However, Lloyd's sign is specifically defined as positive costovertebral angle ...
The costovertebral angle (Latin: arcus costovertebralis) is the acute angle formed on either side of the human back between the twelfth rib and the vertebral column. [ 1 ] The kidney lies directly below this area, so is the place where, with percussion ( Latin : sucussio renalis ), pain is elicited when the person has kidney inflammation .
Murphy's sign has a high sensitivity and negative predictive value, although the specificity is not high. [2] However, in the elderly the sensitivity is markedly lower; a negative Murphy's sign in an elderly person is not useful for ruling out cholecystitis if other tests and the clinical history suggest the diagnosis.
Nephritis can often be caused by infections and toxins, but it is most commonly caused by autoimmune disorders that affect the major organs like kidneys. [5]Pyelonephritis is inflammation that results from a urinary tract infection that reaches the renal pelvis of the kidney.