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A representation of the 3D structure of the microROSE RNA. This derived from a solution NMR structure of the microROSE element. [1]The repression of heat shock gene expression (ROSE) element is an RNA element found in the 5' UTR of some heat shock protein's mRNAs.
Homeothermy is one of the 3 types of thermoregulation in warm-blooded animal species. Homeothermy's opposite is poikilothermy . A poikilotherm is an organism that does not maintain a fixed internal temperature but rather its internal temperature fluctuates based on its environment and physical behaviour.
Thermoregulation is the ability of an organism to keep its body temperature within certain boundaries, even when the surrounding temperature is very different. A thermoconforming organism, by contrast, simply adopts the surrounding temperature as its own body temperature, thus avoiding the need for internal thermoregulation.
Heat shock proteins (HSPs) are a family of proteins produced by cells in response to exposure to stressful conditions. They were first described in relation to heat shock, [1] but are now known to also be expressed during other stresses including exposure to cold, [2] UV light [3] and during wound healing or tissue remodeling. [4]
As in other mammals, human thermoregulation is an important aspect of homeostasis. In thermoregulation, body heat is generated mostly in the deep organs, especially the liver, brain, and heart, and in contraction of skeletal muscles. [1] Humans have been able to adapt to a great diversity of climates, including hot humid and hot arid.
Vasomotor responses allow control of the flow of blood between the periphery and the core to control heat loss from the surface of the body. Lastly, the organism can show insulation adjustments; a common example being "goosebumps" in humans where hair follicles are raised by pilomotor muscles, also shown in animals' pelage and plumage. [4]
The honey bee, for example, does so by contracting antagonistic flight muscles without moving its wings (see insect thermoregulation). [ 18 ] [ 19 ] [ 20 ] This form of thermogenesis is, however, only efficient above a certain temperature threshold, and below about 9–14 °C (48–57 °F), the honey bee reverts to ectothermy.
A similar example is given by the Senegalese sole (Solea senegalensis), which, when acclimated to temperatures of 26 °C, produced a significantly higher amount of taurine, glutamate, GABA and glycine compared to acclimation to 12 °C. This may mean that the aforementioned compounds aid in antioxidant defense, osmoregulatory processes, or ...