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On the other hand, as of 2015 the price of topical (non-oral) treatment with efinaconazole was $2307 per nail, so testing is recommended before prescribing it. [21] The cost of efinaconazole treatment can be reduced to $65 per 1-month dose using drug coupons, bringing the treatment cost to $715 per nail. [40]
This condition may follow certain diseases such as syphilis, or can result from fever, trauma, systemic upsets or adverse reaction to drugs. Onychorrhexis also known as brittle nails, is brittleness with breakage of fingernails or toenails. Paronychia is a bacterial or fungal infection where the nail and skin meet.
Onychorrhexis (from the Greek words ὄνυχο- ónycho-, "nail" and ῥῆξις rhexis, "bursting"), is a brittleness with breakage of finger or toenails that may result from hypothyroidism, anemia, anorexia nervosa or bulimia, or after oral retinoid therapy. [1]: 786 It can also be seen in melanoma that involves the nail and onychomycosis. [2]
Efinaconazole, sold under the brand name Jublia among others, is a triazole antifungal medication. It is approved for use in the United States, Canada, and Japan as a 10% topical solution for the treatment of onychomycosis (fungal infection of the nail). [3] [4] Efinaconazole acts as a 14α-demethylase inhibitor. [5] [2]
The following is a list of antibiotics. The highest division between antibiotics is bactericidal and bacteriostatic. Bactericidals kill bacteria directly, whereas bacteriostatics prevent them from dividing. However, these classifications are based on laboratory behavior.
Antibiotics may be used after the procedure but are not recommended, as they may delay healing. [10] Surgical treatment for ingrown nails is more effective at preventing the nail from regrowing inwards compared to non-surgical treatments. [14] A toe following wedge resection with an image of the nail removed
Given the popularity of GLP-1 drugs and the potential for an oral GLP-1 drug launch in 2026, Lilly remains very well positioned. As such, I think the stock still looks attractive at current levels.
Other potential treatments that could be helpful are urea pastes with a 40% or greater concentration, electric drills, and nail avulsion. In complex situations or those with recurrences, chemical or surgical matricectomy may be used as a last resort to accomplish permanent ablation of the affected nail plate.