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Fulminant (/ ˈ f ʊ l m ɪ n ən t /) is a medical descriptor for any event or process that occurs suddenly and escalates quickly, and is intense and severe to the point of lethality, i.e., it has an explosive character. [1] The word comes from Latin fulmināre, to strike with lightning. There are several diseases described by this adjective:
Fulminates were discovered by Edward Charles Howard in 1800. [1] [2] [3] The use of fulminates for firearms was first demonstrated by a Scottish minister, Alexander John Forsyth, who patented his scent-bottle lock in 1807; this was a small container filled with fulminate of mercury.
Fulminant infection from meningococcal bacteria in the bloodstream is a medical emergency and requires emergent treatment with vasopressors, fluid resuscitation, and appropriate antibiotics. Benzylpenicillin was once the drug of choice with chloramphenicol as a good alternative in allergic patients. Ceftriaxone is an antibiotic commonly ...
2020: “A case of fulminant sepsis caused by Capnocytophaga canimorsus after a dog bite.” [29] 2018: “Purpura Fulminans and Septic Shock due to Capnocytophaga Canimorsus after Dog Bite: A Case Report and Review of the Literature.” [ 30 ]
Marburg variant of MS is an acute fulminant demyelinating process which in most cases progresses inexorably to death within 1–2 years. [12] However, there are some reports of Marburg MS reaching stability by three years. [13]
Fulminant hepatitis, or massive hepatic cell death, is a rare and life-threatening complication of acute hepatitis that can occur in cases of hepatitis B, D, and E, in addition to drug-induced and autoimmune hepatitis.
This fulminant type is associated with severe symptoms (usually diarrhea, rectal bleeding and abdominal pain) and is usually associated with systemic symptoms including fever. [13] It is associated with a high mortality rate as compared to milder forms of UC, with a 3-month and 12 month mortality rate of 0.84% and 1% respectively. [ 13 ]
Acute liver failure is the appearance of severe complications rapidly after the first signs (such as jaundice) of liver disease, and indicates that the liver has sustained severe damage (loss of function of 80–90% of liver cells).