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Neuropathic pain is pain caused by a lesion or disease of the somatosensory nervous system. [2] [3] Neuropathic pain may be associated with abnormal sensations called dysesthesia or pain from normally non-painful stimuli . It may have continuous and/or episodic components. The latter resemble stabbings or electric shocks.
Peripheral neuropathy may be classified according to the number and distribution of nerves affected (mononeuropathy, mononeuritis multiplex, or polyneuropathy), the type of nerve fiber predominantly affected (motor, sensory, autonomic), or the process affecting the nerves; e.g., inflammation (), compression (compression neuropathy), chemotherapy (chemotherapy-induced peripheral neuropathy).
Nerve compression syndrome, or compression neuropathy, or nerve entrapment syndrome, is a medical condition caused by chronic, direct pressure on a peripheral nerve. [1] It is known colloquially as a trapped nerve , though this may also refer to nerve root compression (by a herniated disc , for example).
Central pain syndrome, also known as central neuropathic pain, [1] is a neurological condition consisting of constant moderate to severe pain due to damage to the central nervous system (CNS) which causes a sensitization of the pain system. [2] [3] The extent of pain and the areas affected are related to the cause of the injury. [4]
The oculomotor nerve controls all the muscles that move the eye except for the lateral rectus and superior oblique muscles. It also serves to constrict the pupil and open the eyelid. The onset of a diabetic third nerve palsy is usually abrupt, beginning with frontal or pain around the eye and then double vision. All the oculomotor muscles ...
Since peripheral anaesthesia of the injured sciatic nerve after the development of pain-related behaviours was also found to attenuate thermal hyperalgesia in CCI rats, dextrorphan or ketamine treatment, alone or in combination with local nerve anaesthesia, may prove to be a useful therapeutic means for clinical management of neuropathic pain ...