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Some genetic conditions that result in a "leucistic" appearance include piebaldism, Waardenburg syndrome, vitiligo, Chédiak–Higashi syndrome, flavism, isabellinism, xanthochromism, axanthism, amelanism, and melanophilin mutations. Pale patches of skin, feathers, or fur (often referred to as "depigmentation") can also result from injury.
Type 4 is caused by a mutation in any of a range of genes, the most common being SOX10, when it is classed as type 4C. Type 4A is caused by an autosomal dominant or autosomal-recessive mutation in the gene EDNRB. [15] Type 4B is caused by an autosomal dominant or autosomal-recessive mutation in the gene EDN3. [27]
Vitiligo (/ ˌ v ɪ t ɪ ˈ l aɪ ɡ oʊ /, vi-ti-leye-goh) is a chronic autoimmune disorder that causes patches of skin to lose pigment or color. [1] The cause of vitiligo is unknown, but it may be related to immune system changes, genetic factors, stress, or sun exposure. [5] [6] Treatment options include topical medications, light therapy ...
It causes depigmentation of the skin (and fur). These photos beautifully capture how vitiligo has made Buster even more unique: November 2021, November 2022, August 2023, and April 2024. Image ...
Vitiligo is a condition that causes the skin to begin to lose its pigmentation—or color—for no apparent reason, resulting in white patches that are especially noticeable in people whose skin ...
Multiple-gene inheritance of genodermatosis refers to the inheritance of a skin disease caused by multiple genetic abnormalities. [2] Cases of skin disease that may be inherited in this mode include vitiligo, psoriasis, pemphigus vulgaris, systemic lupus erythematosus and so on. [2] [8]