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  2. Field cancerization - Wikipedia

    en.wikipedia.org/wiki/Field_cancerization

    The field defect adjacent to a colon cancer consists of the inner surface of the colon (the epithelium) that has about 1 million crypts (indentations in the surface of the epithelium). [21] Each crypt has about 5,000 cells in the shape of a test-tube and all 5,000 cells of the crypt are generated from the few stem cells at the base of the crypt.

  3. Colorectal cancer - Wikipedia

    en.wikipedia.org/wiki/Colorectal_cancer

    Colorectal cancer (CRC), also known as bowel cancer, colon cancer, or rectal cancer, is the development of cancer from the colon or rectum (parts of the large intestine). [5] Signs and symptoms may include blood in the stool , a change in bowel movements , weight loss, abdominal pain and fatigue. [ 9 ]

  4. Colon cancer staging - Wikipedia

    en.wikipedia.org/wiki/Colon_cancer_staging

    The T stages of bowel cancer. Numbers 0 to 4, with subgroups, are used to describe deepest tumor depth: [2] TX: The primary tumor cannot be evaluated. T0: No evidence of cancer in the colon or rectum. Tis: Carcinoma in situ; Cancer cells are found only in the epithelium or lamina propria; T1: Growth into the submucosa; T2: Growth into the ...

  5. Mouse model of colorectal and intestinal cancer - Wikipedia

    en.wikipedia.org/wiki/Mouse_model_of_colorectal...

    Furthermore, when evaluated for ERCC1, beclin-1, and beta-catenin in the stem cell region of crypts, the colonic tissues of chlorogenic acid-fed mice showed amelioration of the molecular aberrancies, [29] suggesting that chlorogenic acid is protective at the molecular level against colon cancer. This is the first diet-related model of colon ...

  6. Malignant transformation - Wikipedia

    en.wikipedia.org/wiki/Malignant_transformation

    Colon cancer provides one example of the mechanisms by which diet, the top factor listed in the table, is an external factor in cancer. The Western diet of African Americans in the United States is associated with a yearly colon cancer rate of 65 per 100,000 individuals, while the high fiber/low fat diet of rural Native Africans in South Africa is associated with a yearly colon cancer rate of ...

  7. A 34-year-old teacher finally got on 'Jeopardy!' after 15 ...

    www.aol.com/lifestyle/34-old-teacher-finally-got...

    He has stage IV colon cancer. Natalie Rahhal. November 21, 2024 at 3:52 PM. ... It's becoming more common for young adults to have colorectal cancer — and to find out at later stages.

  8. Cancer staging - Wikipedia

    en.wikipedia.org/wiki/Cancer_staging

    Colon cancer: originally consisted of four stages: A, B, C, and D (the Dukes staging system). More recently, colon cancer staging is indicated either by the original A-D stages or by TNM. [8] Kidney cancer: uses TNM. [9] Cancer of the larynx: Uses TNM. [10] Liver cancer: Uses TNM. [11] Lung cancer: uses TNM. [12] Melanoma: TNM used. Also of ...

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