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MHC Class II molecules are a class of major histocompatibility complex (MHC) molecules normally found only on professional antigen-presenting cells such as dendritic cells, macrophages, some endothelial cells, thymic epithelial cells, and B cells. These cells are important in initiating immune responses.
Class I – Items of subsistence, e.g., food and forage, which are consumed by personnel or animals at an approximately uniform rate, irrespective of local changes in combat or terrain conditions. Class II – Supplies for which allowances are established by tables of organization and equipment, e.g., clothing, weapons, tools, spare parts ...
Class II MHC molecules are also heterodimers, genes for both α and β subunits are polymorphic and located within MHC class II subregion. The peptide-binding groove of MHC-II molecules is formed by the N-terminal domains of both subunits of the heterodimer, α1 and β1, unlike MHC-I molecules, where two domains of the same chain are involved.
Class II may refer to: Class II antiarrhythmic; Class II appliance; Class II bacteriocin; Class II cabinet; Class II electrical appliance; Class II gaming; Class II gene;
Chemical classification systems attempt to classify elements or compounds according to certain chemical functional or structural properties. Whereas the structural properties are largely intrinsic, functional properties and the derived classifications depend to a certain degree on the type of chemical interaction partners on which the function is exerted.
The study of molecules by molecular physics and theoretical chemistry is largely based on quantum mechanics and is essential for the understanding of the chemical bond. The simplest of molecules is the hydrogen molecule-ion, H 2 +, and the simplest of all the chemical bonds is the one-electron bond.
Group I: great danger, and most protective packaging required. Some combinations of different classes of dangerous goods on the same vehicle or in the same container are forbidden if one of the goods is Group I. [7] Group II: medium danger; Group III: minor danger among regulated goods, and least protective packaging within the transportation ...
Class II – high permeability, low solubility. Example: glibenclamide, bicalutamide, ezetimibe, aceclofenac; The bioavailability of those products is limited by their solvation rate. A correlation between the in vivo bioavailability and the in vitro solvation can be found. Class III – low permeability, high solubility . Example: cimetidine