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Human infectious diseases may be characterized by their case fatality rate (CFR), the proportion of people diagnosed with a disease who die from it (cf. mortality rate).It should not be confused with the infection fatality rate (IFR), the estimated proportion of people infected by a disease-causing agent, including asymptomatic and undiagnosed infections, who die from the disease.
The mortality rate from sepsis, especially if it is not treated rapidly with the needed medications in a hospital, is approximately 40% in adults and 25% in children. It is significantly greater when sepsis is left untreated for more than seven days. [36]
For the Netherlands, based on overall excess mortality, an estimated 20,000 people died from COVID-19 in 2020, [10] while only the death of 11,525 identified COVID-19 cases was registered. [9] The official count of COVID-19 deaths as of December 2021 is slightly more than 5.4 million, according to World Health Organization's report in May 2022 ...
By April 25, the U.S. had more than 905,000 confirmed coronavirus cases and nearly 52,000 deaths, giving it a mortality rate around 5.7 percent. (In comparison, Spain's mortality rate was 10.2 percent and Italy's was 13.5 percent.) [87] [88] In April 2020, more than 10,000 American deaths had occurred in nursing homes.
In a small study of 26 decedents, [better source needed] the pandemized COVID-19 and infection-related disease were "major contributors" to patients' death. [12] Such deaths are sometimes evaluated via excess deaths per capita – the COVID-19 pandemic deaths between January 1, 2020, and December 31, 2021, are estimated to be ~18.2 million ...
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Sepsis occurs in 1–2% of all hospitalizations and accounts for as much as 25% of ICU bed utilization. Due to it rarely being reported as a primary diagnosis (often being a complication of cancer or other illness), the incidence, mortality, and morbidity rates of sepsis are likely underestimated. [30]
Left untreated, bubonic plague will have a CFR of up to 60%. [21]: 57 With antibiotic treatment, the CFR for bubonic plague is 17%, pneumonic 29% and septicaemic 45%. [22] [23] Active tuberculosis, the infection with the highest mortality rate, has a CFR of 43% in the absence of HIV. [24] [25]