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Lower urinary tract infections may involve the bladder (cystitis) or urethra while upper urinary tract infections affect the kidney (pyelonephritis). [10] Symptoms from a lower urinary tract infection include suprapubic pain, painful urination ( dysuria ), frequency and urgency of urination despite having an empty bladder. [ 1 ]
Sepsis is caused by many organisms including bacteria, viruses, and fungi. [10] Common locations for the primary infection include the lungs, brain, urinary tract, skin, and abdominal organs. [2] Risk factors include being very young or old, a weakened immune system from conditions such as cancer or diabetes, major trauma, and burns. [1]
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Urosepsis is defined as sepsis caused by a urogenital tract infection and comprises about 25% of all sepsis cases. [18] Urosepsis is the result of a systemic inflammatory response to infection and can be identified by numerous signs and symptoms (e.g. fever, hypothermia, tachycardia, and leukocytosis). [18]
It may occur in the case of diseases of the urinary tract, reproductive system and diseases of the abdominal organs. [6] Leukocyturia is mostly a sign of urinary tract infection, especially if significant bacteriuria is found (for most people, the number of bacteria in a culture is > 10^5) and other symptoms associated with passing urine. [7]
Risk factors include sexual intercourse, prior urinary tract infections, diabetes, structural problems of the urinary tract, and spermicide use. [2] [3] The mechanism of infection is usually spread up the urinary tract. [2] Less often infection occurs through the bloodstream. [1] Diagnosis is typically based on symptoms and supported by ...