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The chemokine (C-X-C motif) ligand 1 (CXCL1) is a small peptide belonging to the CXC chemokine family that acts as a chemoattractant for several immune cells, especially neutrophils [5] [6] or other non-hematopoietic cells to the site of injury or infection and plays an important role in regulation of immune and inflammatory responses. It was ...
The CC chemokine (or β-chemokine) proteins have two adjacent cysteines (amino acids), near their amino terminus. There have been at least 27 distinct members of this subgroup reported for mammals, called CC chemokine ligands -1 to -28; CCL10 is the same as CCL9. Chemokines of this subfamily usually contain four cysteines (C4-CC chemokines ...
CCL2 is a small cytokine that belongs to the CC chemokine family. CCL2 tightly regulates cellular mechanics [ 5 ] and thereby recruits monocytes , memory T cells , and dendritic cells to the sites of inflammation produced by either tissue injury or infection .
Stromal cell-derived factors 1-alpha and 1-beta are small cytokines that belong to the chemokine family, members of which activate leukocytes and are often induced by proinflammatory stimuli such as lipopolysaccharide, TNF, or IL1. The chemokines are characterized by the presence of 4 conserved cysteines that form 2 disulfide bonds. They can be ...
CCL1 is involved in inflammatory processes through leukocyte recruitment and could play a crucial role in angiogenesis and other viral and tumoral processes. [10] [11] [12] For example, CCL1 transcription was increased in primary human CD4 + T cells expressing T cell immunoglobulin and protein 3 containing the mucin domain (TIM-3) and was identified as a differentially transcribed gene in CD4 ...
Chemokine (C-X-C motif) ligand 9 (CXCL9) is a small cytokine belonging to the CXC chemokine family that is also known as monokine induced by gamma interferon (MIG). The CXCL9 is one of the chemokine which plays role to induce chemotaxis , promote differentiation and multiplication of leukocytes , and cause tissue extravasation.
6375 16963 Ensembl ENSG00000143184 ENSMUSG00000026573 UniProt P47992 P47993 RefSeq (mRNA) NM_002995 NM_008510 RefSeq (protein) NP_002986 NP_032536 Location (UCSC) Chr 1: 168.58 – 168.58 Mb Chr 1: 164.76 – 164.76 Mb PubMed search Wikidata View/Edit Human View/Edit Mouse Chemokine (C motif) ligand (XCL1) is a small cytokine belonging to the C chemokine family that is also known as ...
Chemokine (C-X-C motif) ligand 16 (CXCL16) is a small cytokine belonging to the CXC chemokine family. Larger than other chemokines (with 254 amino acids ), CXCL16 is composed of a CXC chemokine domain, a mucin -like stalk, a transmembrane domain and a cytoplasmic tail containing a potential tyrosine phosphorylation site that may bind SH2 .