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  2. HLA-DQ2 - Wikipedia

    en.wikipedia.org/wiki/HLA-DQ2

    HLA-DQ2 (DQ2) is a serotype group within HLA-DQ (DQ) serotyping system. The serotype is determined by the antibody recognition of β 2 subset of DQ β-chains. The β-chain of DQ is encoded by HLA-DQB1 locus and DQ2 are encoded by the HLA-DQB1 *02 allele group. This group currently contains two common alleles, DQB1 *0201 and DQB1 *0202.

  3. Autoimmune polyendocrine syndrome type 2 - Wikipedia

    en.wikipedia.org/wiki/Autoimmune_polyendocrine...

    HLA(haplotypes) In terms of genetics one finds that autoimmune polyendocrine syndrome type 2 has an autosomal dominant pattern of inheritance, with an incomplete penetrance. [ 7 ] [ 8 ] Furthermore, the human leukocyte antigen involved in this condition are HLA-DQ2(DR3 (DQB*0201)) and HLA-DQ8(DR4 (DQB1*0302)), [ 9 ] genetically speaking , which ...

  4. HLA-DQ - Wikipedia

    en.wikipedia.org/wiki/HLA-DQ

    An example of a serotype is DQ2. Recognize HLA-DQB1*02 gene products which include gene products of the following alleles: HLA-DQB1*02:01; HLA-DQB1*02:02; HLA-DQB1*02:03; Sometimes DQ2 antibodies recognize other gene products, such as DQB1*03:03, resulting in serotyping errors. Because of this mistyping serotyping is not as reliable as gene ...

  5. Human leukocyte antigen - Wikipedia

    en.wikipedia.org/wiki/Human_leukocyte_antigen

    HLA region of Chromosome 6. The human leukocyte antigen (HLA) system is a complex of genes on chromosome 6 in humans that encode cell-surface proteins responsible for regulation of the immune system. [1] The HLA system is also known as the human version of the major histocompatibility complex (MHC) found in many animals. [2]

  6. Gluten immunochemistry - Wikipedia

    en.wikipedia.org/wiki/Gluten_immunochemistry

    Alpha gliadin is composed of repeated motifs that, when digested, can be presented by HLA-DQ molecules. DQ2.5 recognizes several motifs in gluten proteins, and therefore HLA-DQ can recognize many motifs on each gliadin (see Understanding DQ haplotypes and DQ isoforms on the right) [18] However, numbers of different proteins from the grass tribe ...

  7. History and naming of human leukocyte antigens - Wikipedia

    en.wikipedia.org/wiki/History_and_naming_of...

    Sensitivity can be improved by knowing the haplotype. In Europe, HLA-A1 is strongly linked to a 'chunk of chromosome' called a 'haplotype'. This haplotype, Super-B8, is A1-Cw7-B8-DR3-DQ2, about 2 million DNA codons (the nucleotide building blocks) long. This chunk has avoided recombination for thousands of years.

  8. Flu, COVID and RSV vaccines are here. Here's your go-to ... - AOL

    www.aol.com/lifestyle/flu-covid-rsv-vaccines...

    Flu: CDC also recommends that everyone 6 months and older get an annual flu shot, “with rare exception” (i.e., if you’ve had a severe allergic reaction to a flu vaccine in the past, or if ...

  9. HLA DR3-DQ2 - Wikipedia

    en.wikipedia.org/wiki/HLA_DR3-DQ2

    HLA DR3-DQ2 is the serotypic representation of a HLA-DRB1:DQA1:DQB1 cis-chromosomal haplotype on human 6p21.3 in a region known as the HLA complex. The DR3-DQ2 haplotype is notable because of the very strong linkage between genes that extends into the HLA-A , - B and - C regions of the HLA gene complex in northern and northwestern Europe.