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Sometimes before, but especially after being fed the pelican chick may seem to "throw a tantrum" by loudly vocalizing and dragging itself around in a circle by one wing and leg, striking its head on the ground or anything nearby and the tantrums sometimes end in what looks like a seizure that results in the chick falling briefly unconscious ...
Kindling is a commonly used model for the development of seizures and epilepsy in which the duration and behavioral involvement of induced seizures increases after seizures are induced repeatedly. [1] Kindling is also referred as an animal visual model of epilepsy that can be produced by focal electrical stimulation in the brain.
The Australian pelican (Pelecanus conspicillatus) is a large waterbird in the family Pelecanidae, widespread on the inland and coastal waters of Australia and New Guinea, also in Fiji, parts of Indonesia and as a vagrant in New Zealand. It is a predominantly white bird with black wings and a pink bill.
Domoic acid is a neurotoxin that inhibits neurochemical processes, causing short-term memory loss, brain damage, and, in severe cases, death in humans. In marine mammals, domoic acid typically causes seizures and tremors. Studies have shown that there are no symptomatic effects in humans at levels of 0.5 mg/kg of body weight.
Epileptogenesis that occurs in human brains has been modeled in a variety of animal models and cell culture models. [2] Epileptogenesis is poorly understood, [6] and increasing understanding of the process may aid researchers in preventing seizures, diagnosing epilepsy, [23] and developing treatments to prevent it. [2]
A seizure is a paroxysmal episode of symptoms or altered behavior arising from abnormal excessive or synchronous brain neuronal activity. [5] A focal onset seizure arises from a biological neural network within one cerebral hemisphere, while a generalized onset seizure arises from within the cerebral hemispheres rapidly involving both hemispheres.