Ads
related to: nucleoside reverse transcriptase inhibitors mechanism of action kidney- About PH1
Discover an FDA-approved treatment
for patients with PH1.
- Patient Brochure
Help your patients
understand their condition.
- Dosing & Administration
See dosage and administration info
for an available PH1 treatment.
- Clinical Data
Review clinical trial data for an
available PH1 treatment.
- Fill Out the Start Form
Fill out the Start Form to get
access to therapy.
- Efficacy & Safety
Read the efficacy & safety profile
of this treatment option for PH1.
- About PH1
Search results
Results From The WOW.Com Content Network
Nucleoside analog reverse-transcriptase inhibitors (NARTIs or NRTIs) compose the first class of antiretroviral drugs developed. In order to be incorporated into the viral DNA, NRTIs must be activated in the cell by the addition of three phosphate groups to their deoxyribose moiety, to form NRTI triphosphates.
Lamivudine is a nucleoside reverse transcriptase inhibitor and works by blocking the HIV reverse transcriptase and hepatitis B virus polymerase. [1] Lamivudine was patented in 1995 and approved for use in the United States in 1995. [8] [9] It is on the World Health Organization's List of Essential Medicines. [10] It is available as a generic ...
Entecavir is in the nucleoside reverse transcriptase inhibitors (NRTIs) family of medications. [6] [7] It prevents the hepatitis B virus from multiplying by blocking reverse transcriptase. [6] Entecavir was approved for medical use in 2005. [6] It is on the World Health Organization's List of Essential Medicines. [8] It is available as a ...
It is a combination of three medications with different and complementary mechanisms of action: abacavir (reverse transcriptase inhibitor), dolutegravir (integrase inhibitor) and lamivudine (nucleoside analog reverse transcriptase inhibitor). [3]
B: Mechanism of action of the nucleotide analogue reverse-transcriptase inhibitor, tenofovir. Most standard HIV drug therapies revolve around inhibiting the reverse transcriptase enzyme (RT), an enzyme that is necessary to the HIV-1 virus and other retroviruses to complete their life cycle. [5] The RT enzyme serves two key functions.
Reverse-transcriptase inhibitor: ... and 300 mg lamivudine, a nucleoside analogue reverse transcriptase ... resistance to the integrase inhibitor ...