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Baseline vagal tone can be used either as a potential predictor of behavior or as a signal of mental health (particularly emotion regulation, anxiety, and internalizing and externalizing disorders). [28] [29] The polyvagal theory by Porges is an influential model of how the vagal pathways respond to novelty and to stressful external stimuli.
The vagus nerve (/ ˈ v eɪ. ɡ ə s /), also known as the tenth cranial nerve, cranial nerve X, or simply CN X, is a cranial nerve that carries sensory and motor fibers. It creates a pathway that interfaces with the parasympathetic control of the heart, lungs, and digestive tract.
Cranial nerves; CN 0 – Terminal; CN I – Olfactory; CN II – Optic; CN III – Oculomotor; CN IV – Trochlear; CN V – Trigeminal; CN VI – Abducens; CN VII – Facial; CN VIII – Vestibulocochlear; CN IX – Glossopharyngeal; CN X – Vagus; CN XI – Accessory; CN XII – Hypoglossal
Thus, the prefrontal input to the ANS modulate the inflammatory response to psychological stress in part via the cholinergic anti-inflammatory pathway. [14] In recent years, this PFC-Vagus Nerve-Spleen axis has been linked to cellular senescence [15] [16] and various pathologies such as neurodegenerative diseases and cancer. [17] [18]
The theory has been widely adopted in trauma therapy, where practitioners use its concepts to help patients understand their physiological responses to stress and trauma. Therapists such as Bessel van der Kolk , Peter A. Levine , and others have incorporated elements of PVT into practices like somatic experiencing and trauma-informed care.
The following diagram is provided as an overview of and topical guide to the human nervous system: Human nervous system. Human nervous system – the part of the human body that coordinates a person's voluntary and involuntary actions and transmits signals between different parts of the body.
Mesocortical pathway; Mesolimbic pathway; Nigrostriatal pathway; Tuberoinfundibular pathway; Serotonergic pathways. Raphe Nuclei; Norepinephrine Pathways Locus coeruleus and other noradrenergic cell groups; Epinephrine pathways from adrenergic cell groups; Glutamate and acetylcholine pathways from mesopontine nuclei
Cranial nerves are the nerves that emerge directly from the brain (including the brainstem), of which there are conventionally considered twelve pairs.Cranial nerves relay information between the brain and parts of the body, primarily to and from regions of the head and neck, including the special senses of vision, taste, smell, and hearing.