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Necrotizing fasciitis (NF), also known as flesh-eating disease, is an infection that kills the body's soft tissue. [3] It is a serious disease that begins and spreads quickly. [ 3 ] Symptoms include red or purple or black skin, swelling, severe pain, fever , and vomiting. [ 3 ]
The treatment of choice is penicillin, and the duration of treatment is around 10 days. [23] Antibiotic therapy (using injected penicillin) has been shown to reduce the risk of acute rheumatic fever. [24] In individuals with a penicillin allergy, erythromycin, other macrolides, and cephalosporins have been shown to be effective treatments. [25]
The affected tissue of patients with severe cases of necrotizing fasciitis are devoid of neutrophils. [27] The serine protease ScpC, which is released by S. pyogenes, is responsible for preventing the migration of neutrophils to the spreading infection. ScpC degrades the chemokine IL-8, which would otherwise attract neutrophils to the site of ...
The bacteria, which causes necrotizing fasciitis, has an extremely high mortality rate, and accurate diagnosis, rapid antibiotic administration and prompt surgery are extremely important in ...
The clinical presentation among invasive disease is also dominated by skin and soft tissue infections, including a small subset of patients presenting with severe necrotizing fasciitis. [1] [2] Moreover, it is an important cause of bone and joint infections, and this disease manifestation is reported to be increasing. [12]
If an abscess is also present, surgical drainage is usually indicated, with antibiotics often prescribed for co-existent cellulitis, especially if extensive. [17] Pain relief is also often prescribed, but excessive pain should always be investigated, as it is a symptom of necrotizing fasciitis. Elevation of the affected area is often recommended.
Dry, wet, gas, internal, necrotizing fasciitis [3] Risk factors: Diabetes, peripheral arterial disease, smoking, major trauma, alcoholism, plague, HIV/AIDS, frostbite, Raynaud's syndrome [3] [4] Diagnostic method: Based on symptom, With medical imaging used to identify the underlying cause. Treatment: Depends on underlying cause [5] Prognosis ...
An Indianapolis woman died after what looked like a pimple turned out to be a case of necrotizing fasciitis or flesh-eating bacteria, which she allegedly contracted while on vacation. Here ...