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Chlorhexidine [1] is a disinfectant and antiseptic with the molecular formula C 22 H 30 Cl 2 N 10, which is used for skin disinfection before surgery and to disinfect surgical instruments. [2] It is also used for cleaning wounds , preventing dental plaque , treating yeast infections of the mouth , and to keep urinary catheters from blocking. [ 3 ]
Since 1987, octenidine has been used in Europe as an antiseptic, in concentrations of 0.1 to 2.0%. [citation needed] It is a substitute for chlorhexidine, with respect to its slow action and concerns about the carcinogenic impurity 4-chloroaniline.
Chlorhexidine is an antibacterial agent that covers a wide spectrum of gram-positive and gram-negative bacteria. Rinsing with 15 ml of a 0.12% or 10 ml of 0.2% chlorhexidine solution for 30 seconds produced large and prolonged reductions in salivary bacterial counts within 7 hours of its use.
Most mares with acute endometritis recover spontaneously. Recommended therapy is to infuse the uterus with an antibiotic such as penicillin, cleansing the clitoral area with 2% chlorhexidine solution and then applying chlorhexidine or nitrofurazone ointment to the clitoral fossa and sinuses. The entire treatment is repeated daily for five days.
cationic surfactants, such as 0.05–0.5% benzalkonium, 0.5–4% chlorhexidine, 0.1–2% octenidine solutions. Others are generally not applicable as safe antiseptics, either because of their corrosive or toxic nature.
Chlorhexidine digluconate is a chemical antiseptic and is used in a 0.05–0.2% solution as a mouthwash. [ 54 ] [ 11 ] [ 45 ] [ 55 ] There is no evidence to support that higher concentrations are more effective in controlling dental plaque and gingivitis. [ 56 ]
It was first discovered and developed by ICI and introduced under the brand name Cetavlon. [2] It is used as a 1-3 % solution for cleaning roadside accident wounds. [3] ICI also introduced Savlon, which was a combination of cetrimide and chlorhexidine. ICI later sold the Savlon brand OTC to Johnson & Johnson in May 1992. [4]
Listerine (/ ˈ l ɪ s t ər iː n /) is a brand of antiseptic mouthwash that is promoted with the slogan "Kills germs that cause bad breath". Named after Joseph Lister, who pioneered antiseptic surgery at the Glasgow Royal Infirmary in Scotland, Listerine was developed in 1879 by Joseph Lawrence, a chemist in St. Louis, Missouri.
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