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  2. Explainer-Why are US pharmacy benefit managers under fire? - AOL

    www.aol.com/news/explainer-why-us-pharmacy...

    Pharmacy benefit managers (PBMs) are in the crosshairs of Republicans and Democrats in Congress but have so far dodged any new litigation or reforms that had been targeted for inclusion in last ...

  3. Pharmacy benefit management - Wikipedia

    en.wikipedia.org/wiki/Pharmacy_benefit_management

    As of 2023, PBMs managed pharmacy benefits for 275 million Americans and the three largest PBMs in the US, CVS Caremark, Cigna Express Scripts, and UnitedHealth Group’s Optum Rx, make up about 80% of the market share covering about 270 million people [4] [5] with a market of almost $600 billion in 2024.

  4. Amid increased federal scrutiny, PBMs pivot strategy to ... - AOL

    www.aol.com/finance/amid-increased-federal...

    Pharmacy benefits managers (PBMs) are employing new strategies to squeeze independent pharmacies, even as the industry faces pressure from the federal government, which is looking for ways to curb ...

  5. Management of depression - Wikipedia

    en.wikipedia.org/wiki/Management_of_depression

    With more chronic forms of depression, the most effective treatment is often considered to be a combination of medication and psychotherapy. [6] [9] Psychotherapy is the treatment of choice in people under 18. [8] A meta-analysis examined the effectiveness of psychotherapy for depression across ages from younger than 13 years to older than 75 ...

  6. Breakthrough antidepressants with fewer side effects could ...

    www.aol.com/finance/breakthrough-antidepressants...

    The number of people with depression has reached new highs—and so has antidepressant use. As Americans are increasingly reaching for pharmaceutical solutions for depression—about one in eight ...

  7. Biology of depression - Wikipedia

    en.wikipedia.org/wiki/Biology_of_depression

    There is some evidence that there is decreased nigrostriatal pathway activity in people with melancholic depression (psychomotor retardation). [42] Further supporting the role of dopamine in depression is the consistent finding of decreased cerebrospinal fluid and jugular metabolites of dopamine, [ 43 ] as well as post mortem findings of ...

  8. Antidepressants and suicide risk - Wikipedia

    en.wikipedia.org/wiki/Antidepressants_and...

    Antidepressants could increase the risk of suicidal thoughts and behavior in people with depression under the age of 25. In 2004, the U.S. Food and Drug Administration along with the Neuro-Psychopharmacologic Advisory Committee and the Anti-Infective Drugs Advisory Committee, concluded that there was a causal link between newer antidepressants and pediatric suicidality. [7]

  9. Medicare Prescription Drug, Improvement, and Modernization Act

    en.wikipedia.org/wiki/Medicare_Prescription_Drug...

    Medicare Modernization Act — includes PDF file of the actual text of the law. Medicare.gov — the official website for people with Medicare Medicare Modernization Act at Medicare.gov; Prescription Drug Coverage homepage at Medicare.gov — a central location for Medicare's web-based information about the Part D benefit