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The single repeatable side effect of oral megadose vitamin C is a mild laxative effect if the practitioner attempts to consume too much too quickly. In the United States and Canada, a tolerable upper intake level (UL) was set at 2,000 mg/day, citing this mild laxative effect as the reason for establishing the UL. [ 1 ]
Specific medical names of the different conditions are derived from the given vitamin involved: an excess of vitamin A, for example, is called hypervitaminosis A. Hypervitaminoses are primarily caused by fat-soluble vitamins ( D and A ), as these are stored by the body for longer than the water-soluble vitamins.
Vitamin C supplements among other dietary supplements at a US drug store. Vitamin C has a definitive role in treating scurvy, which is a disease caused by vitamin C deficiency. Beyond that, a role for vitamin C as prevention or treatment for various diseases is disputed, with reviews often reporting conflicting results.
[2] [3] It is generally accepted that doses of any vitamin greatly in excess of nutritional requirements will result either in toxicity (vitamins A and D) or in the excess simply being metabolised; thus evidence in favour of vitamin supplementation supports only doses in the normal range.
Vitamin D toxicity, or hypervitaminosis D, is the toxic state of an excess of vitamin D.The normal range for blood concentration of 25-hydroxyvitamin D in adults is 20 to 50 nanograms per milliliter (ng/mL).
Vitamin products above these regulatory limits are not considered supplements and should be registered as prescription or non-prescription (over-the-counter drugs) due to their potential side effects. The European Union, United States and Japan establish ULs. [11] [59] [60]
Side effects from vitamin overdoses may occur, especially in patients with kidney failure. In very large doses, vitamin C in kidney-failure patients can cause severe side effects such as oxalate deposits in bone and soft tissues and may interfere with the absorption and metabolism of vitamin B 12. The product contains 1 g of vitamin C per ...
Intravenous Ascorbic Acid or PAA, pharmacologic ascorbic acid [1] (also known as vitamin C or L-ascorbic acid), is a process that delivers soluble ascorbic acid directly into the bloodstream. It is not approved for use to treat any medical condition.