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A megakaryoblast (from mega- 'large' karyo- 'cell nucleus' and -blast 'precursor cell') is a precursor cell to a promegakaryocyte. During thrombopoiesis , the promegakaryocyte matures into the form of a megakaryocyte .
Acute megakaryoblastic leukemia (AMKL) is life-threatening leukemia in which malignant megakaryoblasts proliferate abnormally and injure various tissues. Megakaryoblasts are the most immature precursor cells in a platelet-forming lineage; they mature to promegakaryocytes and, ultimately, megakaryocytes which cells shed membrane-enclosed particles, i.e. platelets, into the circulation.
CFU-Meg (hematopoietic stem cell/hemocytoblast) → megakaryoblast → promegakaryocyte → megakaryocyte. Megakaryocytes are derived from hematopoietic stem cell precursor cells in the bone marrow. They are produced primarily by the liver, kidney, spleen, and bone marrow.
The megakaryoblast is a platelet precursor that undergoes endomitosis to form megakaryocytes that have 8 to 64 nuclei. Megakaryocytes shed platelets into the bloodstream. β1-tubulin microtubules, which are found in megakaryocytes, facilitate this process of shedding platelets into the bloodstream. [5]
Promegakaryocyte. A promegakaryocyte is a precursor cell for a megakaryocyte, the development of which proceeds as follows: [1]. CFU-Meg (hematopoietic stem cell/hemocytoblast) → megakaryoblast → promegakaryocyte → megakaryocyte
The yeast mitochondrial code; The mold, protozoan, and coelenterate mitochondrial code and the mycoplasma/spiroplasma code; The invertebrate mitochondrial code; The ciliate, dasycladacean and hexamita nuclear code; The deleted kinetoplast code; cf. table 4. deleted, cf. table 1. The echinoderm and flatworm mitochondrial code; The euplotid ...
CFU-GEMM is a colony forming unit that generates myeloid cells.CFU-GEMM cells are the oligopotential progenitor cells [1] [2] for myeloid cells; they are thus also called common myeloid progenitor cells or myeloid stem cells.
Leukopoiesis is a form of hematopoiesis in which white blood cells (WBC, or leukocytes) are formed in bone marrow located in bones in adults and hematopoietic organs in the fetus.