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The parahippocampal gyrus (or hippocampal gyrus [1]) is a grey matter cortical region of the brain that surrounds the hippocampus and is part of the limbic system. The region plays an important role in memory encoding and retrieval. It has been involved in some cases of hippocampal sclerosis. [2] Asymmetry has been observed in schizophrenia. [3]
The uncus is an anterior extremity of the parahippocampal gyrus.It is separated from the apex of the temporal lobe by a sulcus called the rhinal sulcus. [1] Although superficially continuous with the hippocampal gyrus, the uncus forms morphologically a part of the rhinencephalon.
With its medial boundary corresponding approximately to the rhinal sulcus it is located primarily in the fusiform gyrus.Cytoarchitecturally it is bounded laterally and caudally by the inferior temporal area 20, medially by the area 35 and rostrally by the temporopolar area 38 (H) (Brodmann-1909).
The EC is located in the parahippocampal gyrus, [22] a cortical region adjacent to the hippocampus. [28] This gyrus conceals the hippocampus. The parahippocampal gyrus is adjacent to the perirhinal cortex, which plays an important role in the visual recognition of complex objects. There is also substantial evidence that it makes a contribution ...
View of left entorhinal cortex (red) from beneath the brain, with front of brain at top. Artist's rendering. The superficial layers – layers II and III – of EC project to the dentate gyrus and hippocampus: Layer II projects primarily to dentate gyrus and hippocampal region CA3; layer III projects primarily to hippocampal region CA1 and the subiculum.
Area 27 of Brodmann-1909 is a cytoarchitecturally defined cortical area that is a rostral part of the parahippocampal gyrus.It is commonly regarded as a synonym of presubiculum.
While many of the connections in non-human primates may be present in humans, they are less well documented. Studies have shown strong reciprocal connections to medial temporal lobe memory structures, such as the entorhinal cortex and the parahippocampal gyrus, the latter being involved in associative learning and episodic memory. [6]
In human anatomy, the piriform cortex has been described as consisting of the cortical amygdala, uncus, and anterior parahippocampal gyrus. [1] More specifically, the human piriform cortex is located between the insula and the temporal lobe, anteriorly and laterally of the amygdala. [2] [3]