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Microcephaly generally is due to the diminished size of the largest part of the human brain, the cerebral cortex, and the condition can arise during embryonic and fetal development due to insufficient neural stem cell proliferation, impaired or premature neurogenesis, the death of neural stem cells or neurons, or a combination of these factors ...
Clinically, patients present with microcephaly and significant developmental delay. While some patients may be able to walk, others may not due to spasticity of limbs and hypotonic muscle tone, with progressive degeneration over time. Patients may also present with seizures, ranging from single febrile seizure to intractable epilepsy.
Certain mutations in MCPH1, when homozygous, cause primary microcephaly—a severely diminished brain. [ 5 ] [ 6 ] [ 7 ] Hence, it has been assumed that variants have a role in brain development. [ 8 ] [ 9 ] However, in normal individuals no effect on mental ability or behavior has yet been demonstrated in either this or another similarly ...
Kernicterus causes yellow pigmentation of the skin, brain damage, and deafness. [65] Petechaie is when the capillaries bleed resulting in red/purple spots on the skin. [66] However, cytomegalovirus is often fatal in the embryo. The Zika virus can also be transmitted from the pregnant mother to her baby and cause microcephaly. [citation needed]
Guillain–Barré syndrome, during pregnancy can cause microcephaly in the baby [4] [5] [6] Duration: Short-term [2] Causes: Zika virus mainly spread by mosquitoes, can also be sexually transmitted [2] Diagnostic method: Testing blood, urine, or saliva for viral RNA or blood for antibodies [1] [2] Differential diagnosis
Beka Setzer, an Ohio mother of two young daughters, took to Facebook last summer to share shocking photos of her daughter Emmalee's legs after a day spent playing outside went awry. "PSA," she wrote.
Other topicals include crotamiton and sulfur ointment for treating scabies in young children and pregnant women. Prescription medicine can kill scabies but the itch may persist for weeks after that.
Encephaloceles are often accompanied by craniofacial abnormalities or other brain malformations. Symptoms may include neurologic problems, hydrocephalus (cerebrospinal fluid accumulated in the brain), spastic quadriplegia (paralysis of the limbs), microcephaly (an abnormally small head), ataxia (uncoordinated muscle movement), developmental delay, vision problems, mental and growth retardation ...