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Progressive supranuclear palsy (PSP) is a late-onset neurodegenerative disease involving the gradual deterioration and death of specific volumes of the brain. [1] [2] The condition leads to symptoms including loss of balance, slowing of movement, difficulty moving the eyes, and cognitive impairment. [1]
PSP has been all over the news—here's what to know about it.
They include multiple system atrophy (MSA), progressive supranuclear palsy (PSP), and corticobasal degeneration (CBD). Dementia with Lewy bodies (DLB), may or may not be part of the PD spectrum, but it is increasingly recognized as the second-most common type of neurodegenerative dementia after Alzheimer's disease.
Eventually, mutism and progressive dementia set in. [2] Parkinsonism can be the first symptom of the disease, and it is noteworthy that some FTDP-17 patients have been misdiagnosed with Parkinson's disease or sporadic progressive supranuclear palsy. However, in some families, the parkinsonism appears later in the progression of the illness or ...
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Progressive supranuclear palsy (PSP) is a type of tauopathy, but the cause is not yet discovered. For PSP unusual phosphorylation for tau protein causes vital protein filaments in the nerve cells to destruct, a phenomenon called "neurofibrillary" degeneration.